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Avastin (Roche) Anti Cancer Medicines
Avastin (bevacizumab) is a cancer medicine that interferes with the growth and spread of cancer cells in the body.
Avastin is used to treat a certain type of brain tumor, and certain types of cancers of the kidney, lung, colon, rectum, cervix, ovary, or fallopian tube.
Avastin is also used to treat cancer of the membrane lining the internal organs in your abdomen. It is usually given as part of a combination of cancer medicines.
What Avastin is used for:
Treatment of metastatic colon or rectal cancer, used as part of a combination chemotherapy regimen.
Treatment for non-squamous, non-small cell lung cancer.
Treatment of metastatic breast cancer used as part of a combination chemotherapy regimen.
Treatment of glioblastoma (GBM).
Treatment of metastatic renal cell carcinoma.
How Avastin is given:
Avastin is given through an infusion into a vein (intravenous, IV). The first dose is given over 90 minutes. The infusion time can eventually be shortened to 30 minutes if well-tolerated.
The amount of avastin that you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer or condition being treated. Your doctor will determine your dose and schedule.
Side effects of Avastin:
Important things to remember about the side effects of avastin:
Most people do not experience all of the side effects listed.
Side effects are often predictable in terms of their onset and duration.
Side effects are almost always reversible and will go away after treatment is complete.
There are many options to help minimize or prevent side effects.
There is no relationship between the presence or severity of side effects and the effectiveness of the medication.
There is no data as to the frequency of adverse reactions that may be attributed to avastin alone. (In clinical studies avastin was used in combination with other chemotherapy medications).
The following side effects are common (occurring in greater than 30%) for patients taking avastin:
Nausea & vomiting
Upper respiratory infection
Low white blood cell count. (This can put you at increased risk for infection.)
Proteinuria (see kidney problems)
Nose bleed (see bleeding problems)